R Thomas Taggart, Ignacio del Castillo. GJB2: The spectrum on Deafness- Causing Allele Variants and Their Phenotype. Human Mutation 2004;24:305-311. 48. Ignacio del Castillo, Manuela Villamar, Miguel A. Moreno Pelayo, Francisco J. del Castillo, Araceli Álvarez, Dolores Telleria. A Deletion Involving the Connexin 30 Gene in Nonsyndromic Hearing impairment. N Engl J Med 2002; 346: 4. 49. Ignacio del Castillo, Miguel A. Moreno Pelayo, Francisco J. del Castillo, Zippora Brownstein, Sandrine Marlin, Quint Adina. Prevalence and Evolutionary Origins of the del(GJB6-D13S1830) Mutation in the DFNB1 Locus in Hearing-impaired Subjects: a Multicenter Study. Am. J. Hum. Genet. 2003;73:1452-1458. 50. Cynthia C. Morton Ph.D and Walter E. Nance M.D. Newborn Hearing Screening A Silent Revolution. N Engl J Med 2006;354:20. 51. del Castillo IV, Moreno-Pelayo MA, del Castillo FJ, Alvarez A, Telleria D, Menendez I, Moreno F (2002) A deletion involving the connexin 30 gene in nonsyndromic hearing impairment. N Engl J Med 346:243– 249. 52. F. J. del Castillo, M Rodríguez Ballesteros, A Álvarez Hutchin, E Leonardi, C A de Oliveira, H Azaiez, Z Brownstein. A novel deletion involving the connexin-30 gene, del (GJB6-d13s1854), found in trans with mutations in the GJB2 gene (connexin-26) in subjects with DFNB1 non-syndromic hearing impairment. J Med Genet 2005;42:588-594. 53. René Utrera, Vanessa Ridaura, Yuryanni Rodríguez, Maria J. Rojas, Leomig Mago, Simón Angeli And Oswaldo Henríquez. Detection of the 35delG/GJB2 and del(GJB6-D13S1830 )Mutations in Venezuelan Patients with Autosomal Recessive Nonsyndromic Hearing Loss GENETIC TESTING Volume 11, Number 4, 2007 58 54. Juan Rodriguez-Paris, Iris Schrijver. The digenic hypothesis unraveled: The GJB6 del(GJB6-D13S1830) mutation causes allele- specific loss of GJB2 expression in cis. Biochemical and Biophysical Research Communications 389 (2009) 354–359 55. Padma G., Ramchander P. V., Nandur U. V. and Padma T. 2009 GJB2 and GJB6 gene mutations found in Indian probands with congenital hearing impairment. J. Genet. 88, 267–272. 56. Melissa de Freitas Cordeiro-Silva 1, Andressa Barbosa 2, Marília Santiago 3, Mariana Provetti 4, Eliete Rabbi- Bortolini Prevalence of 35delG/GJB2 and del (GJB6-D13S1830) mutations in patients with non-syndromic deafness from a population of Espírito Santo - Brazil Braz J Otorhinolaryngol. 2010; 76(4):428-32. Portada Índice I. Siglas y Abreviaturas II. Resumen III. Antecedentes IV. Planteamiento del Problema y Justificación V. Objetivo VI. Hipótesis VII. Diseño del Estudio VIII. Materiales y Métodos IX. Aspectos Éticos y de Bioseguridad X. Análisis Estadístico XI. Resultados XII. Discusión XIII. Conclusiones XIV. Referencias