Diabetes Melitus-35

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Natural History of Diabetes
Years of Diabetes
*IGT = impaired glucose 
tolerance.
Obesity IGT* Diabetes Uncontrolled 
Hyperglycemia
Relative -Cell 
Function
100 (%)
-20 -10 0 10 20 30
Plasma
Glucose
Insulin Resistance
Insulin Secretion
120 (mg/dL)
Adapted from International Diabetes Center (IDC), Minneapolis, Minnesota.
Fasting Glucose
Post-Meal 
Glucose
Natural History of Type 2 Diabetes