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How is the transmission of the action potential from the axon to the muscle fibers produced? The action potential that reaches the presynaptic ter...

How is the transmission of the action potential from the axon to the muscle fibers produced?

The action potential that reaches the presynaptic terminal causes its depolarization, which triggers the opening of calcium channels and allows the entry of this ion.
The increase in calcium concentration causes about 200 to 300 vesicles to adhere to the synaptic cleft and release their content into it.
Acetylcholine (Ach) is synthesized in the presynaptic buttons from choline and acetyl-CoA, by the action of choline acetyltransferase formed in the neuronal soma and transported to the nerve terminal.
The Ach synthesized is stored inside the synaptic vesicles, each of which contains approximately 10,000 to 50,000 Ach molecules.
The Ach released binds to its specific receptor located on the postsynaptic membrane, causing its depolarization.
The Ach binding to its corresponding receptor changes the permeability of the postsynaptic membrane to ions.
The Ach molecule is degraded by acetylcholinesterase in the synaptic cleft, which is essential to prevent the 'permanent' contraction of muscle fibers.
The postsynaptic membrane potential generated by the Ach binding to its receptor is called the motor end plate potential.
The motor end plate potential acts as a stimulus to generate an action potential in the adjacent membrane, which allows the molecular phenomena that produce muscle contraction to be triggered.
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