What factors determine the activation and differentiation of virgin T lymphocytes into Th1, Th2 or regulatory lymphocytes?
The type of PAMP locate...
What factors determine the activation and differentiation of virgin T lymphocytes into Th1, Th2 or regulatory lymphocytes?
The type of PAMP located on the pathogenic microorganism and the receptors that recognize it. The cytokines secreted by inflammatory cells such as dendritic cells, NK cells, macrophages, and others. The predominance of IFN-γ and IL-12 cytokines, for example, in viral infections. The exposure to antigens without PAMP does not generate effector T lymphocytes, but induces regulatory T lymphocytes. a) I and II are correct. b) II and III are correct. c) I, II, and III are correct. d) II, III, and IV are correct.