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This book is printed on acid-free paper. 0 Copyright © 1993 by ACADEMIC PRESS, INC. All Rights Reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Academic Press, Inc. 1250 Sixth Avenue, San Diego, California 92101-4311 United Kingdom Edition published by Academic Press Limited 24-28 Oval Road, London NW1 7DX Library of Congress Cataloging-in-Publication Data Molecular mechanisms of immunological self-recognition / edited by Frederick W. Alt and Henry J. Vogel, p. cm. Includes index. ISBN 0-12-053750-8 1. Immunological tolerance. 2. Cellular recognition. 3. T cells. 4. B cells. I. Alt, Frederick W. II. Vogel, Henry J. (Henry James), date. [DNLM: 1. Autoimmunity. 2. B-Lymphocytes-immunology. 3. Cell Communication. 4. Immune Tolerance. 5. T-Lymphocytes-immunology. QW568M7186] QR188.4.M65 1993 616.07'9-<lc20 DNLM/DLC for Library of Congress 92-49201 CIP Printed in MEXICO 92 93 94 95 96 97 DO 9 8 7 6 5 4 3 2 1