What is the patogenia of myofascial syndrome?

I- The PG is caused by a dysfunction of the motor plate.
II- A neuropathy/radiculopathy produces hypersensitivity to acetylcholine.
III- The excessive activation of the membrane by acetylcholine leads to maximum contractile activity on the trigger point.
IV- The contraction knots are the result of continuous maximum contractile activity of a group of contracted sarcomeres.
a) I and II are correct.
b) II and III are correct.
c) II, III, and IV are correct.