What factors should be considered when determining the dose of antineoplastic drugs for a patient?
Age, general health status, concomitant medications, hepatic and renal function, pharmacokinetics and pharmacodynamics variability, cachexia, obesity, and other concomitant conditions
Sequence of drug administration, size of the commercialized vial of the antineoplastic, and previous response to treatment
Type of cancer, stage of the disease, and patient's weight